The house is located Darb al-Labana Lane, and is considered one of the best-preserved structures exhibiting domestic architecture of the eighteenth century. It was popularly known as the House of Artists because many artists, such as Ragheb Ayyad and Shadi Abd al-Salam, resided there.
Ali Labib House was first established by Umar al-Malatili and his brother Ibrahim and it was was later known as Ali Labib.
The house was neglected towards the end of the 20th century until it was renovated at the turn of the millennium. In the 21st century, Ali Labib House was converted into a museum of architecture, and is where the House of Egyptian Architecture is based.